Calcium dobesilate is a vasoprotective. It is the calcium salt of dobesilic acid. It is a synthetic molecule with the ability to reduce capillary permeability in the body. Calcium dobesilate is indicated in states of fragility and altered capillary permeability and in diabetic retinopathy. In combination with lidocaine or with lidocaine and dexamethasone , the drug enters the composition of preparations for the therapy of hemorrhoidal disease.